Archief Roodbont

Bisphosphonates are widely used for the treatment of bone diseases, including Paget's disease, osteoporosis, hypercalcaemia and malignant bone diseases. Bisphosphonates are active and strong inhibitors of osteoclast activity.^[4] Besides these effects on bone, bisphosphonates also possess antiinflammatory properties, explaining therapeutic trials in inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and ankylosing spondylitis.We discuss the relevance of the use of bisphosphonates in ankylosing spondylitis based upon recently published clinical trial

Antiinflammatory Treatment With Bisphosphonates in Ankylosing Spondylitis