Thursday, August 23, 2007
CRP C-reactive protein
http://www.clinicalgeriatrics.com/article/7609
CONCLUSION
Persons over 65 years of age are at increased risk
for cardiovascular disease, regardless of their
cholesterol levels. C-reactive protein, an inflam-
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Clinical Geriatrics Volume 15, Number 8 August 2007
C - R E A C T I V E P R O T E I N A N D C A R D I O V A S C U L A R R I S K
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matory marker, and potentially a mediator of
atherosclerotic disease, has been shown to have
predictive value that is independent of LDL-C,
and perhaps even superior to that of LDL-C.
Clinically, measurement of CRP may best be
used at this time in primary prevention patients
with moderate-to-high risk and average levels of
LDL-C to help refine degree of risk and best
treatment options. Treatment with statins has
been shown to provide superior risk reduction in
patients with elevated levels of CRP.
Dr. Blaine has received grant support, is a consultant
for, and is a member of the speaker’s bureau of
AstraZeneca; is on the speaker’s bureau of Merck and
Pfizer; and is a consultant for Daiichi Sankyo, Inc.