Archief Roodbont

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In this study, fish oil capsules containing omega-3 fatty acids effectively lowered the AA:EPA ratio in both healthy and CAD patients. Several studies have found that lowering the AA:EPA ratio improved CAD outcomes, including the Study on Prevention of Coronary Atherosclerosis by Intervention with Marine Omega-3 Fatty Acids (SCIMO), the Lyon Diet Heart Study, and the Physician's Health Study.^[1-3] Specifically, the Lyon Diet Heart Study found that a 30% reduction in the AA:EPA ratio was associated with a 70% reduction in the risk for myocardial infarction.^[2]

The US Food and Drug Administration recently approved a prescription form of omega-3 fatty acids as an adjunct to treatment of very high (≥ 500 mg/dL) triglyceride levels.^[4] In this study, triglyceride levels in the CAD patients did not decrease after receiving omega-3 fatty acids. However, the study did not reveal whether any of the CAD participants had "very" high triglyceride levels. A larger and longer prospective study including CAD patients with documented "high" triglyceride levels may demonstrate lipid profile effects from omega-3 fatty acids.

# posted by roodbont @ 2:25 PM