Archief Roodbont

Plos biology vol 5 issue11
nov 2007 27-11-2007

Gek of heilig is vaak geen groot verschil

Taken together, these results indicate that Fabp7 is responsible for differences in the animals' PPI responses and that the gene plays a vital role in brain development. Given the link between in utero malnutrition and increased risk for schizophrenia, the researchers reason that dysregulation of Fabp7 and lipid metabolism during development may cause long-term changes in gene expression, explaining an excess of Fabp7 in the schizophrenic cortex. Whether Fabp7 operates alone or with other genes on Chromosome 10 must be explored in future studies. And while no methods to prevent schizophrenia exist, the researchers recommend designing cohort studies to find out whether supplementing the diets of pregnant mothers in high-risk families with DHA proves beneficial.