Saturday, February 28, 2009
testosterone en A.F,
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Low Testosterone Levels Associated With Lone Atrial Fibrillation in Men
Reuters Health Information 2009. © 2009 Reuters Ltd.
Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.
By Will Boggs, MD
NEW YORK (Reuters Health) Feb 20 - Reduced testosterone levels in men may increase the risk of lone atrial fibrillation (AF), according to a report in the January issue of Clinical Cardiology.
"Since AF is associated with significant morbidity and mortality, it may be important to discriminate those who are susceptible to AF by some certain biomarkers such as C-reactive protein, brain natriuretic peptide, endothelin-1, and maybe testosterone," Dr. Jiangtao Lai from School of Medicine Zhejiang University, Hangzhou, China, told Reuters Health.
Dr. Lai and colleagues examined whether testosterone and estradiol levels differed between 58 men with lone AF and 58 healthy men matched by age, race, and ethnicity.
Mean testosterone levels in men with lone AF were significantly lower than those in healthy controls, the authors report, but mean estradiol levels did not differ significantly between the 2 groups.
In a logistic regression analysis, sex hormone levels, age, body mass index, and blood pressure were not independent predictors of lone AF.
"We can't say that testosterone predicts lone AF since this was a relatively small sample study and this might potentially lead to spurious findings," Dr. Lai said. "We plan to investigate the possible association between testosterone level and the risk for lone AF in more subjects, more strictly designed studies, or prospective studies if possible."
Clin Cardiol 2009;32:43-46.
Low Testosterone Levels Associated With Lone Atrial Fibrillation in Men
Reuters Health Information 2009. © 2009 Reuters Ltd.
Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.
By Will Boggs, MD
NEW YORK (Reuters Health) Feb 20 - Reduced testosterone levels in men may increase the risk of lone atrial fibrillation (AF), according to a report in the January issue of Clinical Cardiology.
"Since AF is associated with significant morbidity and mortality, it may be important to discriminate those who are susceptible to AF by some certain biomarkers such as C-reactive protein, brain natriuretic peptide, endothelin-1, and maybe testosterone," Dr. Jiangtao Lai from School of Medicine Zhejiang University, Hangzhou, China, told Reuters Health.
Dr. Lai and colleagues examined whether testosterone and estradiol levels differed between 58 men with lone AF and 58 healthy men matched by age, race, and ethnicity.
Mean testosterone levels in men with lone AF were significantly lower than those in healthy controls, the authors report, but mean estradiol levels did not differ significantly between the 2 groups.
In a logistic regression analysis, sex hormone levels, age, body mass index, and blood pressure were not independent predictors of lone AF.
"We can't say that testosterone predicts lone AF since this was a relatively small sample study and this might potentially lead to spurious findings," Dr. Lai said. "We plan to investigate the possible association between testosterone level and the risk for lone AF in more subjects, more strictly designed studies, or prospective studies if possible."
Clin Cardiol 2009;32:43-46.
# posted by roodbont @ 3:36 AM 
