Saturday, September 04, 2010
statins
The results of the meta-analysis will be formally presented this week here at the European Society of 2010 Cardiology Congress and were presented early to the media during an afternoon press conference.
Included in the data were 21 studies, including more than 130 000 patients, comparing statins vs placebo controls, and five studies, with approximately 40 000 patients, examining different statin doses. Overall, there was no risk of cancer with statin therapy, and there was no increased risk observed among patients treated with higher statin doses. Numerically, the number of patients who developed cancer was nearly identical in the statin and control arms and in the statin trials comparing higher vs lower doses.
In addition, there was no increased incidence of cancer when investigators analyzed the rates of disease among patients by baseline LDL-cholesterol levels, including levels <77 mg/dL, or by duration of treatment. Similarly, there was no increased risk of any specific types of cancer, such as breast, prostate, bladder, or hematological cancers.
Included in the data were 21 studies, including more than 130 000 patients, comparing statins vs placebo controls, and five studies, with approximately 40 000 patients, examining different statin doses. Overall, there was no risk of cancer with statin therapy, and there was no increased risk observed among patients treated with higher statin doses. Numerically, the number of patients who developed cancer was nearly identical in the statin and control arms and in the statin trials comparing higher vs lower doses.
In addition, there was no increased incidence of cancer when investigators analyzed the rates of disease among patients by baseline LDL-cholesterol levels, including levels <77 mg/dL, or by duration of treatment. Similarly, there was no increased risk of any specific types of cancer, such as breast, prostate, bladder, or hematological cancers.
# posted by roodbont @ 1:09 AM 
