Thursday, August 04, 2011

 

gout jicht

NSAIDs

NSAIDs are the usual first-line treatment for gout, and no specific agent is significantly more or less effective than any other.[2] Improvement may be seen within 4 hours, and treatment is recommended for 1–2 weeks.[2][6] They are not recommended, however in those with certain other health problems, such as gastrointestinal bleeding, renal failure, or heart failure.[33] While indomethacin has historically been the most commonly used NSAID, an alternative, such as ibuprofen, may be preferred due to its better side effect profile in the absence of superior effectiveness.[16] For those at risk of gastric side effects from NSAIDs, an additional proton pump inhibitor may be given.[34]


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